Which of the following is a method used to prepare elixirs?

• A. Simple solution with agitation
• B. Distillation
• C. Freeze-drying
• D. Evaporation

Answer: (A)

Elixirs are clear, sweetened hydroalcoholic solutions in which the drug is dissolved to form a uniform liquid dosage form. The preparation centers on making a simple solution: dissolve the drug in a suitable hydroalcoholic solvent, then add sugar, flavoring, and other additives with agitation until everything is completely dissolved and evenly dispersed. This agitation is key to achieving a homogeneous elixir with the intended potency and taste.

Distillation separates components by boiling and condensing vapors, which is not how an elixir is formed. Freeze-drying removes water to make a solid powder, which defeats the liquid nature of an elixir. Evaporation can concentrate a solution but is not the standard method for creating an elixir and can alter drug stability and potency; it’s not how the final dosage form is built.