Under what condition are capacity markings accurate enough for measuring and dispensing a manufactured liquid product?

• A. Always accurate
• B. Only if the strength of the product is not dependent on the accuracy of the capacity markings
• C. Not accurate at all
• D. Only for extremely dilute solutions

Answer: (B)

Capacity markings are reliable only when the final strength of the liquid does not depend on drawing an exact volume. If the product’s potency is defined in a way that the delivered dose is independent of small variations in how much liquid is measured (for example, a unit-dose container or a situation where the dose is fixed by labeling rather than by volume), then the markings can be considered accurate enough for measuring and dispensing. However, if the dose is determined by the amount of liquid drawn (mg per mL times mL), then any inaccuracy in the capacity markings would lead to a corresponding error in the delivered dose, which is not acceptable. The other options imply universal accuracy, no accuracy at all, or relevance only to very dilute solutions, which do not reflect how dose accuracy depends on the relationship between volume and strength.